SUMMARY: This is a handwritten
response to a request for an autograph from the Mayo Clinic.
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Philip Showalter Hench (1896 - 1965) was an American
physician who, with E. C. Kendall, in 1948 successfully applied
an adrenal hormone (later known as cortisone) in the treatment
of rheumatoid arthritis. With Kendall and Tadeus Reichstein of
Switzerland, Hench received the Nobel Prize for Physiology or
Medicine in 1950 for discoveries concerning hormones of the adrenal
cortex, their structure and biological effects.This offering
in a 3 in by 5 in card signed, Cordial greetings to Judge
Brande from Philip Showater Hench, M.D., Rochester Minnesota,
At the time, the introduction
of cortical streroids into clinical medicine laid the foundation
for the use of these compounds as treatment for not only rheumatoid
arthritis but also for a variety of other diseases that have
as thgeir basic pathology severe inflammation of the affected
tissues. Therefore, the discovery by Hench and his colleagues
was a very important development that stimulated research that
has led to the introduction of modern anti-inflammatory compounds
like Motrin and Celebrex.