SUMMARY: This offering is a First
Day Cover SIGNED by Charles Huggins, M.D. Nobel
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Charles Breton Huggins (1901
- 1997). Hugginswas a Canadian-born American physician
and physiologist and cancer researcher specializing in prostate
cancer.His basic research in castrate dogs showed that the size
and rate of growth of the canine prostate was influenced by male
hormone.This observation eventually led to the treatment of advanced
cancer of the prostate by either castration or the administration
of female hormones. He and Peyton Rous were awarded the 1966
Nobel Prize for Physiology or Medicine. Rous was the co-recipient
of the Nobel for discovering the Rous sarcoma virus in
fowl. Huggins's work led to further clinical investigations in
other human cancers including cancer of the breast where it was
shown that these cancers are also female hormone-dependent.Thus
the work of Huggins led to the clinical understanding that the
growth of human cancers may be influenced by hormone levels in
the blood or the hormonal environment of the cancer.It was the
concept that you couls influence the growth of human cancers
by altering their hormonal environment was the reason Huggins
ws awarded the nobel Prize.
This listing is a 1978 First
Day Cover that is signed Charles Huggins. There
is some very light penciled words far above and below the signature
and on the back top of the envelope that does not affect his
signature.
